Why do some people bounce back from trauma while others stay broken? Armand DiMele traces resilience to genetics, specifically the 5-HTTLPR serotonin transporter gene, exploring how allele variations shape depression risk across individuals and racial groups, with callers sharing their own struggles to recover.
Why do people lie to themselves, and what does that cost them? Armand DiMele and guests Dr. Kent Robertshaw, MD and Stephanie D’Ambra, LCSW explore how shame, unmet needs, and fear of self-examination keep people stuck in dysfunctional patterns, and why honest self-reflection is the foundation of real change.
Estrogen isn’t just a reproductive hormone but a neurotransmitter shaping mood, pain, memory, and brain health. Nutritionist Roberta Maria Achi joins Armand DiMele to explain why carelessly manipulating hormone levels, through drugs or surgery, can have far-reaching consequences, and what diet can do instead.
Armand DiMele and Dr. Kent Robertshaw, MD, Psychiatrist, walk through the landscape of psychiatric medications, from why Prozac reshaped treatment to how a psychiatrist actually chooses between antidepressants based on symptoms. They cover OCD, paranoia, psychosis, and the tension between medication and talk therapy.
One in three American teenagers quits high school, and Armand DiMele and Dr. Kent Robertshaw, MD, Psychiatrist, trace why: boredom, family poverty, drug money, and a school system that mistakes college-prep drilling for real education. The conversation broadens into adult avoidance and the pharmaceutical industry’s role in suppressing discomfort rather than addressing its roots.
Rough childhoods don’t just wound emotionally, they physically reshape the brain, and that is the root of impulse control problems. Armand DiMele and co-host Roberta Maria Atti trace how early neglect stunts neuronal development and drives behaviors from theft and violence to binge eating and self-cutting, with a striking detour into what starvation studies reveal about compulsion.
Armand DiMele traces impulsive behavior from everyday impulse buying and advertising to serious disorders including mania, antisocial personality, and addiction. He argues that reduced sensitivity to consequences is the common thread, and that awareness alone is a powerful first antidote.
Depression is not a benign mood but an active, brain-damaging condition, and cheering someone up is the wrong approach. Armand DiMele explains why depressed people respond to pain and negativity rather than pleasure, and how validating rather than contradicting a depressed person can open a way through.
Andrew Solomon, author of ‘The Noonday Demon,’ joins Armand DiMele to explore how depression escalates across repeated episodes, why agitated depression is especially dangerous, what cortisol does to brain cells over time, and why our screen-saturated, sleep-deprived culture may be quietly fueling an epidemic.
Almost every healing practice, from acupuncture to aromatherapy to the doctor’s waiting room, shares one active ingredient: roughly 22 minutes of enforced stillness. Armand DiMele argues that most human behavior is fear-driven, and that quieting the body temporarily relieves that fear, regardless of what treatment claims to be doing the work.
