In this episode, host Armand DiMele discusses the fascinating relationship between hormones and addiction, particularly focusing on how estrogen affects addiction in women. Joined by science writer Emily Anthes, they explore recent research that reveals significant differences in how addiction manifests in men and women due to hormonal influences. The conversation delves into the evolutionary aspects of addiction, the role of hormones like progesterone and testosterone, and the implications for treatment and understanding of addiction in both genders. The episode highlights the need for gender-specific approaches in addiction treatment and the evolving understanding of parental roles in the context of hormonal changes.