In this episode, Armand DiMele and Roberta Maria Acchi delve into the complexities of depression, exploring its evolutionary roots and societal perceptions. They discuss how depression is often viewed as a weakness, particularly among men, and how societal norms can exacerbate the issue. The conversation touches on Darwinian medicine, the rank theory, and how depression may have served as a survival mechanism in early humans. They also examine the impact of modern societal structures on mental health, including the role of food and lifestyle choices in exacerbating depressive symptoms. The episode aims to provide a deeper understanding of depression as both a personal and collective experience.