In this episode, Armand DiMele explores the intriguing connection between the immune system and mental health. Recent research suggests that infections can influence mood and behavior, potentially triggering conditions like obsessive-compulsive disorder and Tourette’s syndrome. The discussion includes real-life examples, such as the case of a young boy whose personality changed drastically due to a streptococcal infection. DeMille emphasizes the importance of understanding these links, as they could lead to new treatments for various mental health disorders. The episode highlights the evolving view of the brain’s relationship with the immune system and the implications for mental well-being.